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First Opinion is a platform on STAT where experts in the field of life sciences share their thoughts and opinions. Readers can also submit Letters to the Editor in response to these articles for discussion.

In response to Daniel Skovronsky’s defense of the patent system, Savva Kerdemelidis points out that the current system rewards drugs with limited clinical impact, while sidelining more affordable alternatives like generics, nutraceuticals, and lifestyle interventions. Kerdemelidis suggests exploring innovative payer reimbursement models to fund research for cost-effective therapies, creating a sustainable model for medical innovation that focuses on maximizing health impact rather than drug profits.

Regarding the article on asynchronous care by Muthu Alagappan, Rishi Khakhkhar, and Ben Kornitzer, Marc Grella emphasizes the importance of primary care providers having the option to answer patient queries within 24 hours, with separate reimbursement to ensure patient care optimization. Grella suggests insurers should pay for separate physician consultations to reduce the burden on primary care doctors.

Laura and John Arnold’s warning against hospital consolidation is echoed by Moshe Chasky, who highlights the negative impact of hospitals acquiring independent community practices on both physicians and patients. Chasky shares a personal experience where a hospital revoked his inpatient privileges after his practice refused a merger, leading to a loss of continuity of care for his patients. Chasky calls for site-neutral payment reform to level the playing field between physician and hospital payments, allowing independent practices to remain competitive and giving patients more choice in their care.

In conclusion, these responses offer valuable insights into the challenges and potential solutions within the healthcare system, emphasizing the need for innovation, patient-centered care, and equitable reimbursement models to ensure quality care and affordability for all.